She gave her first concert at the age of 10, and there was no looking back - she started giving full-fledged solo concerts which were appreciated by novices and connoisseurs alike. Soon, she was accompanying renowned musicians, both vocalists and instrumentalists. She has performed with her brother and sisters Vid. Srimathi Brahmanandam, also a violinist, and Vid. Padmavathi Anathagopalan, a vainika.
Smt. Rajalakshmi's daughter Dr. Jayanthi Kumaresh is a leading Veena virtuoso and her grandson Abhishek Raghuram, a vibrant and prodigious vocalist.